Persönlicher Status und Werkzeuge

Sprachwahl

Publications of PhD Fellows | 1st Funding Period of the GRK

Viktoria Doll (PhD 5)

Doll V, Ehling-Schulz M, Vogelmann.
Concerted Action of Sphingomyelinase and Non-hemolytic Enterotoxin in Pathogenic Bacillus cereus.
PLoS One, 2013, accepted for publication.

Frenzel E, Doll V, Pauthner M, Lücking G, Scherer S, Ehling-Schulz M. 
CodY orchestrates the expression of virulence determinants in emetic Bacillus cereus by impacting key regulatory circuits.
Mol Microbiol. 2012, 85:67–88

Angela Lindenstrauß (PhD 4)

Lindenstrauss AG, Behr J, Ehrmann MA, Haller D, Vogel RF.
Identifi cation of fi tness determinants in Enterococcus faecalis by differential proteomics.
Arch Microbiol. 2013, 195:121-30.

Lindenstrauss AG, Pavlovic M, Bringmann AE, Behr J, Ehrmann JM, Vogel RF. Comparison of genotypic and phenotypic cluster analyses of virulence determinants and possible role of CRISPR elements towards their incidence in Enterococcus faecalis and  Enterococcus faecium.
Syst Appl Microbiol. 2011, 34: 553-560.

Tim Lubinus  (PhD 5)

Lubinus T,  Barnsteiner A,  Skurk T, Hauner H and Engel K-H
Fate of dietary phytosteryl/-stanyl esters: analysis of individual intact esters in human feces.
Eur J Nutr 2013, 52(3):997-1013.

Barnsteiner A, Lubinus T, di Gianvito A, Schmid W, Engel KH. GC-Based Analysis of Plant Stanyl Fatty Acid Esters in Enriched Foods. J. Agric. Food Chem. 2011, 59: 5204-5214.

Tilo Wünsch (PhD 6)

Wuensch T, Schulz S, Ullrich S, Lill N, Stelzl T, Rubio-Aliaga I, Loh G,
Chamaillard M, Haller D, Daniel H.
The peptide transporter PEPT1 is expressed in distal colon in rodents and humans and contributes to water absorption.
Am J Physiol Gastrointest Liver Physiol. 2013, 305(1):G66 - 73.

Wuensch T, Ullrich S, Schulz S, Chamaillard M, Schaltenberg N, Rath E, Goebel U, Sartor BR, Büning C, Bugert P, Witt H, Haller D, Daniel H.
Colonic expression of the peptide transporter PEPT1 is down-regulated during intestinal inflammation and is not required for NOD2-dependent immune activation.
IBD Journal, 2013, 20(4):671-84.

Natalie Steck (PhD 7)

*Steck N, *Mueller K, Schemann M and Haller D. Bacterial proteases in IBD and IBS.
Gut. 2012, 61:1610-1618.
(*NS and KM are joint first authors)

Steck N, Hoffmann M, Sava IG, Kim SC, Hahne H, Tonkonogy SL, Mair K, Krueger D, Pruteanu M, Shanahan F, Vogelmann R, Schemann M, Kuster B, Sartor RB and Haller D.
Enterococcus faecalis Metalloprotease Compromises Epithelial Barrier and Contributes to Intestinal Inflammation.
Gastroenterology. 2011, 141:959-971.

Marie-Anne von Schillde (PhD 8)

Hörmannsperger G, von Schillde MA, Haller D.
Lactocepin as a protective microbial structure in the context of IBD
Gut Microbes. 2013, 4:152-157

von Schillde MA, Haller D.
Probiotika: Quo vadis...?
Pharmazie in Unserer Zeit 2012, 41:149-153.

von Schillde MA, Hörmannsperger G, Weiher M, Alpert CA, Hahne H, Bäuerl C, van Huynegem K, Steidler L, Hrncir T, Pérez-Martínez G, Küster B, Haller D. Lactocepin Secreted By Lactobacillus Exerts Anti-Inflammatory Effects By Selectively Degrading Proinflammatory Chemokines.
Cell Host & Microbe 2012, 11:387-396.

Kerstin Hartwig, geb. Müller (PhD 9)

*Steck N, *Mueller K, Schemann M and Haller D. Bacterial proteases in IBD and IBS.
Gut. 2012,61:1610-1618
(*NS and KM are joint first authors)

Michel M, Michaelis M, Mazzuoli G, Mueller K, Vanden Berghe P, Schemann M. Fast Calcium and voltage sensitive dye imaging in enteric neurons reveal calcium peaks associated with single action potential discharge.
J Physiol. 2011, 589:5941-5947. 

Mueller K, Michel K, Krueger D, Demir IE, Ceyhan GO, Zeller F, Kreis ME, Schemann M. Activity of protease-activated receptors in the human submucous plexus. Gastroenterology. 2011, 141:2088-2097.    

Krueger D, Foerster M, Mueller K, Zeller F, Slotta-Huspenina J, Donovan J, Grundy D, Schemann M. Signaling mechanisms involved in the intestinal pro-secretory actions of hydrogen sulfide.
Neurogastroenterol Motil. 2010, 22:1224-e320.

Alexander Frank Heiseke (PhD 10)

Heiseke AF, Faul A Cl, Lehr HA, Förster I, Schmid R M, Krug A, Reindl W.
CCL17 promotes intestinal inflammation in mice and counteracts regulatory T cell-mediated protection from colitis.
Gastroenterology. 2012, 142:335-345.

Dominika Kolodziejczak (PhD 11)

Kolodziejczak D, Spanier B, Pais R, Kraiczy J, Stelzl T, Gedrich K, Scherling C, Zietek T, Daniel H.
Mice lacking the intestinal peptide transporter display reduced energy intake and a subtle maldigestion/-absorption that protects them from diet-induced obesity.
Am J Physiol Gastrointest Liver Physiol. 2013, 304(10):G897-907.

Stefan Wagner (PhD 12)

Wagner SJ, Schmidt A, Gruber L, Effenberger MJP, Haller D.
Semi-synthetic diet ameliorates Crohn’s disease-like ileitis in TNF?ARE/WT mice.
Inflamm Bowel Dis. 2013, [Epub ahead of print] doi: 10.1097/ MIB.0b013e31828f573.

Werner T, Wagner SJ, Martínez I, Walter J, Chang JS, Clavel T, Kisling S, Schuemann K, Haller D.
Depletion of luminal iron alters the gut microbiota and prevents Crohn´s disease-like ileitis.
Gut. 2011, 60:325-333.

Schümann K, Becker C, Wagner SJ, Windisch W. Eisen.
In: Praxishandbuch Functional Food. Erbersdobler HF, Mayer AH, (Hrgb)
Behr’s Verlag, 2011, pp 1-39.

Werner T, Wagner SJ, Haller D. Die Bedeutung von Eisen bei chronisch entzündlichen Darmerkrankungen. In: Bauchredner. DCCV e.V.-Mitgliederjournal, Gerd Rieker Verlag, Nackartalfingen, 2010, Heft 1.

Tobias Bauer (PhD 13)

Bauer T, Stark T, Hofmann T, Ehling-Schulz M.
Development of a stable isotope dilution analysis for the quantification of the Bacillus cereus toxin cereulide in foods.
J Agric Food Chem. 2010, 58:1420-1428.

Ramona Pais (PhD 14)

Diakogiannaki E, Pais R, Tolhurst G, Parker HE, Horscroft J, Rauscher B, Zietek T, Daniel H, Gribble FM, Reimann F.
Oligopeptides stimulate glucagon-like peptide-1 secretion in mice through proton-coupled uptake and the calcium-sensing receptor.
Diabetologia. 2013, 56(12):2688-96.

Kolodziejczak D, Spanier B, Pais R, Kraiczy J, Stelzl T, Gedrich K, Scherling C, Zietek T, Daniel H.
Mice lacking the intestinal peptide transporter display reduced energy intake and a subtle maldigestion/-absorption that protects them from diet-induced obesity.
Am J Physiol Gastrointest Liver Physiol. 2013, 304(10):G897-907.

Tobias Ludwig (PhD 15)

Ludwig T, Worsch S, Heikenwalder M, Daniel H, Hauner H, Bader BL.
Metabolic and immunomodulatory effects of n-3 fatty acids are different in mesenteric and epididymal adipose tissue of diet-induced obese mice.
Am J Physiol Endocrinol Metab. 2013, 304.E1140-E1156.

Desmarchelier C, Ludwig T, Scheundel R, Rink N, Bader BL, Klingenspor M, Daniel H.
Diet-induced obesity in ad libitum-fed mice: food texture overrides the effect of macronutrient composition.
Br J Nutr. 2012 Aug 6:1-10.

 

 

Publications of Associated PhD Fellows | 1st Funding Period of the GRK

Emanuel Berger

Chang J-S, Ocvirk S, Berger E, Kisling S, Binder U, Skerra A, Lee AS, Haller D. Endoplasmic reticulum stress response promotes cytotoxic phenotype of CD8??+ intraepithelial lymphocytes in a mouse model for Crohn´s disease-like ileitis.
J Immunol. 2012, Aug 1;189(3):1510-20.

*Rath E, *Berger E, Messlik A, Nunes T, Liu B, Kim SC, Hoggenraad
N, Sans M, Sator RB, Haller D.
Induction of dsRNA-activated protein kinase links mitochondrial unfolded protein response to the pathogenesis of intestinal inflammation.
Gut. 2012, 61:1269-78.
(*RE and BE are joint first authors)

Berger E, Haller D.
Structure-function analysis of the tertiary bile acid TUDCA for the resolution of endo-plasmic reticulum stress in intestinal epithelial cells.
Biochem Biophys Res Commun. 2011, 409:610-615.

Thomas Berger

Buhner S, Li Q, Berger T, Vignali S, Barbara G, De Giorgio R, Stanghellini V, Schemann M.
Submucous rather than myenteric neurons are activated by mucosal biopsy supernatants from irritable bowel syndrome patients.
Neurogastroenterol Motil. 2012 Dec; 24(12):1134-e572. doi: 10.1111/nmo.12011. Epub 2012 Sep 10.

Mena Eidens, geb. Marth

Nässl AM, Rubio-Aliaga I, Fenselau H, Marth MK, Kottra G, Daniel H.
Amino acid absorption and homeostasis in mice lacking the intestinal peptide transporter PEPT1.
Am J Physiol Gastrointest Liver Physiol. 2011, 301:G128-137.

Manuela Sailer

Sailer M, Dahlhoff Ch, Giesbertz P, Eidens MK, de Wit N, Rubio-Aliaga I, Boekschoten M, Müller M, Daniel H.
Increased plasma citrulline in mice marks diet-induced obesity and may predict the development of the metabolic syndrome.
PloS ONE. 2013, accepted for publication.

Dahlhoff C, Desmarchelier C, Sailer M, Fürst RW, Haag A, Ulbrich
SE, Hummel B, Obeid R, Geisel J, Bader BL, Daniel H.
Hepatic methionine homeostasis is conserved in C57BL/6N
mice on a high-fat diet despite major changes in hepatic onecarbon
metabolism.
PlosOne. 2013, 8:e57387. doi:10.1371/ journal.pone.0057387. Epub 2013 Mar 5.

Krug S, Kastenmüller G, Stückler F, Rist MJ, Skurk T, Sailer M, Raffler J, Römisch-Markl W, Adamski J, Prehn C, Frank T, Engel KH, Hofmann T, Luy B, Zimmermann R, Moritz F, Schmitt-Kopplin P, Krumsiek J, Kremer W, Huber F, Oeh U, Theis FJ, Szymczak W, Hauner H, Suhre K, Daniel H.
The dynamic range of the human metabolome revealed by challenges.
FASEB J. 2012, 26:2607-2619.

Desmarchelier C, Dahlhoff C, Keller S, Sailer M, Jahrreis G, Daniel H.
C57BL/6N mice on high fat diet display reduced intestinal and hepatic cholesterol levels despite a plasma hypercholesteroemia.
BMC Genomics. 2012, 13:84.

Nässl AM, Rubio-Aliaga I, Sailer M, Daniel H.
The intestinal peptide transporter PEPT1 is involved in food intake regulation in mice fed a high-protein diet.
PlosOne. 2011, 6(10): e26407. doi:10.1371/journal.pone.0026407.

Rubio-Aliaga I, Roos B, Sailer M, McLoughlin GA, Boekschoten
MV, van Erk M, Bachmair EM, van Schothorst EM, Keijer J, Coort
SL, Evelo C, Gibney MJ, Daniel H, Muller M, Kleemann R, Brennan L.
Alterations in hepatic one-carbon metabolism and related pathways following a high-fat dietary intervention.
Physiol Genomics. 2011, 43:408-16.

Baccini M, Bachmaier EM, Biggeri A, Boekschoten MV, Bouwman FG, Brennan L, Caesar R, Cinti S, Coort SL, Crosley K, Daniel H, Drevon CA, Duthie S, Eijssen L, Elliott RM, van Erk M, Evelo C, Gibney M, Heim C, Horgan GW, Johnson IT,
Kelder T, Kleemann R, Kooistra T, van Iersel MP, Mariman EC, Mayer C, McLoughlin G, Müller M, Mulholland F, van Ommen B, Polley AC, Pujos-Guillot E, Rubio-Aliaga I, Roche HM, de Roos B, Sailer M, Tonini G, Williams LM, de Wit N;
For the NuGO PPS Team.
The NuGO proof of principle study package: a collaborative research effort of the European Nutrigenomics Organisation.
Genes Nutr. 2008, 3:147-151.

Andreas Schlitzer

Schlitzer A, Loschko J, Mair K, Vogelmann R, Henkel L, Einwächter H, Schiemann M, Niess JH, Reindl W, Krug A.
Identification of CCR9- murine plasmacytoid DC precursors with plasticity to differentiate into conventional DCs.
Blood. 2011, 117:6562-6572.

Loschko J, Schlitzer A, Dudziak D, Drexler I, Sandholzer N, Bourquin C, Reindl W, Krug AB.
Antigen Delivery to Plasmacytoid Dendritic Cells via BST2 Induces Protective
T Cell-Mediated Immunity.
J Immunol. 2011, 186: 6718-6725.