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GRK 1482 Jahrbuch 2011-2014

SENIOR PRINCIPAL INVESTIGATORS Page 22 | GRK Progress Report 2011-2014 Education / Degrees 1974 Biology, Chemistry and Physics, Universität Konstanz 1979 Diploma in Biology, ‘excellent’ 1983 Ph.D. in Plant Biochemistry, ’summa cum laude’, Universität Konstanz 1991 Habilitation and venia legendi for Plant Physiology and Microbial Ecology, Universität Konstanz Positions held 1984-1988 Postdoc, Universität Konstanz, Germany 1988/1989 Research Associate, Department of Biochemistry, VirginiaTech, Blacksburg/USA 1989/1990 Research Associate, Universität Konstanz 1991-2002 Associate Professor (C3), Technische Universität München 2000-2003 Member of the Extended Board of Directors, TU München 2003 Full Professor (C4), Technische Universität München, Lehrstuhl für Mikrobielle Ökologie 2003 Managing Director of ZIEL (Zentralinstitut für Ernährungs- und Lebensmittelforschung) 2008 to date Prodekan, Fakultät Wissenschaftszentrum Weihenstephan Research Interests and Achievements Research concentrates on the ecology and molecular genetics of food bor- ne pathogenic bacteria. The following research groups work at the Chair of Microbial Ecology and the Department of Microbiology at ZIEL: 1. Virulence of enteropathegenic Bacillus cereus (Dr. Viktoria Doll) 2. Infection strategies of gut pathogens (Prof. Dr. Thilo M. Fuchs) 3. Emetic toxinformation of Bacillus cereus in food (Dr. Genia Lücking) 4. Molecular Ecology of Listeria (Dr. Stefanie Müller-Herbst) 5. Overlapping genes of pathogenic E. coli (Dr. Klaus Neuhaus) 6. Biodiversity of microbial consortia in industrial habitats (Dr. Mareike Wenning) Achievements: BYK Research Award (1984) Research fellowship of the VW Stiftung (1986) Research fellowship of the DAAD (1988/89) Habilitation fellowship of the DFG (1989/90) Declined C4-offer (‚Ruf’): Veterinary University of Vienna, Austria (2002) Award for Excellent Teaching from the students of Biology, TU München (2005) Otto von Guericke Research Award (2005) Award for Excellent Teaching from the Faculty of Biosciences, TU München (2007) Prof. Dr. Siegfried Scherer Technische Universität München Microbial Ecology (Chair) Weihenstephaner Berg 3, D-85350 Freising - Weihenstephan www.wzw.tum.de/micbio Selected Publications Neuhaus K, Satorhelyi P, Schauer K, Scherer S, Fuchs T. Acid shock of Listeria monocytogenes at low environmental temperatures induces prfA, epithel al cell invasion, and lethality towards Caenorhabditis. BMC Genomics. 2013, in press. Frenzel E, Doll V, Pauthner M, Lücking G, Scherer S, Ehling-Schulz M. CodY orchestrates theexpressionofvirulencedeterminantsinemetic Bacillus cereus by impacting key regulatory circuits. Molecular Microbiology. 2012, 85:67-88. Mir K, Neuhaus K, Scherer S, Bossert M, Schober S. Predicting statistical properties of open reading frames in bacterial genomes. PLoS ONE. (2012), 7(9): e45103. doi:10.1371/ journal.pone.0045103. Bresolin G, Morgan JAW, Ilgen D, Scherer S, Fuchs TM. Low temperature-induced insecticidal activity of Yersinia enterocolitica. Molecular Microbiology. 2006, 59:503-512. Loewe L, Textor V, Scherer S. High deleterious genomic mutation rate in stationary phase of Escherichia coli. Science. 2003, 302:1558-1560. Research Goals How are food borne pathogens adapted to various environmental niches including food and the gastrointestinal tract? What ist the population structure of selec- ted pathogens in the environment and in food? Which hidden genes of pathogens are expressed under various environmental conditions?

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